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Semaglutide vs Tirzepatide
The honest difference
Both are licensed UK medicines with huge trials behind them. In head-to-head studies, tirzepatide gave more weight loss than semaglutide.
Peptide
Semaglutide
Grade A: approved / strong human evidence
Why people buy it
This is the real medicine in Ozempic and Wegovy. People take it to lose weight or to control type 2 diabetes.
Bottom line
A proven medicine that really works. Get it from a doctor or pharmacy, not a website.
- UK status
- A fully licensed UK medicine, prescription-only (POM), regulated by the MHRA. Marketed as Ozempic and Rybelsus (type 2 diabetes) and Wegovy (chronic weight management).
- Sport / WADA
- Not prohibited by WADA; semaglutide and GLP-1 receptor agonists are not on the WADA Prohibited List.
Peptide
Tirzepatide
Grade A: approved / strong human evidence
Why people buy it
This is the real medicine in Mounjaro. People take it to lose weight or to control type 2 diabetes.
Bottom line
A proven medicine that really works. Get it from a doctor or pharmacy, not a website.
- UK status
- Licensed UK medicine. Tirzepatide (brand Mounjaro, Eli Lilly) holds MHRA marketing authorisation for both type 2 diabetes and chronic weight management (broadly, a BMI of 30 or above, or 27 or above with a weight-related comorbidity).
- Sport / WADA
- Not specifically named on the WADA Prohibited List and not a recognised performance-enhancing agent in sport.
Grades are about evidence in humans, not about whether something is right for you. Nothing here is dosing advice. Talk to a qualified clinician before any health decision.
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