Compare
Ipamorelin vs MK-677
The honest difference
Both raise growth hormone. MK-677 is a pill with more human trials, but it still did not make people stronger or healthier.
Peptide
Ipamorelin
Grade C: early / limited human data
Why people buy it
People buy it to build muscle, lose fat, recover faster, sleep better and slow ageing. It makes the body release a burst of its own growth hormone.
Bottom line
It does raise growth hormone in people. Nobody has shown that helps you.
- UK status
- Not a licensed UK medicine and holds no MHRA marketing authorisation.
- Sport / WADA
- Prohibited at all times under WADA category S2 (peptide hormones, growth factors, related substances) as a growth hormone secretagogue / GHS-R agonist.
Peptide
MK-677
Grade B: promising human evidence
Why people buy it
People take it as a pill to raise growth hormone, hoping to build muscle. Sellers often call it a peptide or a 'SARM'. It is neither.
Bottom line
It changes the numbers on a blood test, but did not make people better off. Its maker gave up on it.
- UK status
- Not a licensed medicine in the UK. It has no MHRA marketing authorisation and is not approved as a medicine anywhere in the world.
- Sport / WADA
- Prohibited at all times (in and out of competition) as a growth hormone secretagogue under WADA Prohibited List section S2 (Peptide Hormones, Growth Factors, Related Substances and Mimetics).
Grades are about evidence in humans, not about whether something is right for you. Nothing here is dosing advice. Talk to a qualified clinician before any health decision.
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