Compare
Human Growth Hormone vs MK-677
The honest difference
HGH is a licensed medicine for people who lack growth hormone. MK-677 raises growth hormone as a pill, but its maker abandoned it.
Peptide
Human Growth Hormone
Grade A: approved / strong human evidence
Why people buy it
Doctors prescribe it to children and adults whose bodies do not make enough growth hormone. Online, people buy it to build muscle, lose fat or look younger.
Bottom line
A proven medicine for people who lack growth hormone. For muscle or staying young, studies in people mostly disappoint.
- UK status
- Somatropin is a licensed prescription-only medicine (POM) in the UK, regulated by the MHRA.
- Sport / WADA
- Prohibited at all times (in and out of competition). Growth hormone, its analogues and fragments are listed under WADA Prohibited List section S2.2.3 (Peptide Hormones, Growth Factors, Related Substances and Mimetics).
Peptide
MK-677
Grade B: promising human evidence
Why people buy it
People take it as a pill to raise growth hormone, hoping to build muscle. Sellers often call it a peptide or a 'SARM'. It is neither.
Bottom line
It changes the numbers on a blood test, but did not make people better off. Its maker gave up on it.
- UK status
- Not a licensed medicine in the UK. It has no MHRA marketing authorisation and is not approved as a medicine anywhere in the world.
- Sport / WADA
- Prohibited at all times (in and out of competition) as a growth hormone secretagogue under WADA Prohibited List section S2 (Peptide Hormones, Growth Factors, Related Substances and Mimetics).
Grades are about evidence in humans, not about whether something is right for you. Nothing here is dosing advice. Talk to a qualified clinician before any health decision.
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