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GHK-Cu vs Matrixyl

CC

The honest difference

Both are face-cream ingredients with small, real effects on skin. GHK-Cu is also injected, which nobody has properly tested in people.

Peptide

GHK-Cu

Grade C: early / limited human data

C

Why people buy it

People buy it to make skin look younger, firmer and smoother. Some also inject it, hoping it will repair the whole body and slow ageing.

Bottom line

A reasonable face-cream ingredient with a small effect. The injection story is not proven.

UK status
In the UK, copper tripeptide-1 (GHK-Cu) is widely used and accepted as a cosmetic ingredient, regulated under the GB Cosmetic Products Regulation (retained EU Regulation 1223/2009).
Full GHK-Cu page

Peptide

Matrixyl

Grade C: early / limited human data

C

Why people buy it

It is a face cream ingredient. People use it to reduce fine lines and wrinkles and look younger.

Bottom line

A real but small effect on fine lines. The adverts promise much more than the science shows.

UK status
Matrixyl (palmitoyl pentapeptide-4) is sold legally in the UK as a cosmetic ingredient in topical skincare products.
Sport / WADA
Not relevant / not prohibited. Matrixyl is a topical cosmetic ingredient and does not appear on the WADA Prohibited List.
Full Matrixyl page

Grades are about evidence in humans, not about whether something is right for you. Nothing here is dosing advice. Talk to a qualified clinician before any health decision.

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